
Lymph nodes are crucial components of the immune system. They filter lymph fluid and house immune cells. Humans typically possess between 500 and 800 lymph nodes distributed throughout their bodies. Understanding their specific Lymph Nodes Locations is vital. It helps individuals recognize immune responses, detect infections, and identify potential health issues. This guide provides a clear, comprehensive overview of the major lymph node regions throughout the body. It highlights the significance of these specific locations.
Key Takeaways
Lymph nodes are important parts of your body’s immune system. They filter fluids and fight off sickness.
Lymph nodes are found all over your body. They are in your head, neck, armpits, chest, and groin.
Swollen lymph nodes often mean your body is fighting an infection. Colds or strep throat can cause this.
Some swollen lymph nodes can be a sign of more serious health problems. These include certain cancers.
See a doctor if a swollen lymph node lasts more than two weeks. Also see a doctor if it feels hard or does not move.
Head and Neck Lymph Nodes Locations

The head and neck region contains many lymph nodes. These nodes act as “sentinel sites” for infections in the upper body. They are often the first to show signs of illness. A comprehensive understanding of these nodes includes a cervical lymph node map that extends to 10 levels.
Cervical Lymph Nodes
Cervical lymph nodes are in the neck. They drain lymph from the head, face, scalp, and throat. These nodes include several sub-locations. You can find submental nodes under the chin and submandibular nodes under the jaw. Pre-auricular nodes are in front of the ear, and post-auricular nodes are behind the ear. Occipital nodes are at the back of the head. Superficial and deep cervical nodes run along the sternocleidomastoid (SCM) muscle in the neck.
Many things can cause cervical lymph nodes to swell.
Common infections like the cold, strep throat, or ear infections often lead to swelling.
Dental infections, HIV, and COVID-19 can also cause enlargement.
Other causes include autoimmune diseases, inflammatory conditions, and certain medications.
More serious conditions like lymphoma, certain types of leukemia, or cancers that have spread can also cause swelling in these important Lymph Nodes Locations.
Supraclavicular Lymph Nodes
Supraclavicular lymph nodes are located above the collarbone. They drain lymph from the neck, upper chest, and sometimes the abdomen. When these nodes are palpable, it can signal specific health issues.
For example, a doctor might find these nodes enlarged in cases of:
Lymphoma
Sarcoidosis
Lung cancer, especially bronchogenic carcinoma
Cryptococcus infection
Involvement of supraclavicular nodes often suggests a primary tumor in the lung for lung cancer patients. For HIV-infected patients, Cryptococcus infection can start in these nodes. Effective treatments exist for patients with isolated supraclavicular lymph nodes, even when the primary cancer site is unknown.
Upper Body Lymph Nodes
This section focuses on the lymph nodes of the arms, chest, and armpits. These nodes are important for detecting issues related to the upper limbs and breast health.
Axillary Lymph Nodes
Axillary lymph nodes are located in the armpits. They drain lymph from the arms, breasts, and upper chest wall. Understanding their arrangement helps in medical diagnosis. Anatomists arrange these nodes into six groups:
Anterior (pectoral) group: These nodes lie along the lower border of the pectoralis minor muscle, behind the pectoralis major.
Posterior (subscapular) group: Doctors find these nodes in front of the subscapularis muscle.
Lateral group: These nodes sit along the medial side of the axillary vein.
Central group: This group is in the center of the armpit within the axillary fat.
Infraclavicular (deltopectoral) group: These nodes are not strictly axillary. They lie in the groove between the deltoid and pectoralis major muscles.
Apical group: These nodes are at the top of the armpit, at the lateral border of the first rib.
Surgeons also classify axillary lymph nodes into three levels based on their relationship to the pectoralis minor muscle:
Level I: Nodes are below the lower edge of the pectoralis minor muscle.
Level II: Nodes are underneath or behind the pectoralis minor muscle.
Level III: Nodes are above or medial to the pectoralis minor muscle.
These Lymph Nodes Locations are crucial in breast cancer diagnosis. For example, 45.8% of breast cancer diagnoses involve axillary lymph node metastasis. This includes 26.3% with 1-3 affected nodes, 13.1% with 4-9 affected nodes, and 6.4% with 10 or more affected nodes.
Epitrochlear Lymph Nodes
Epitrochlear lymph nodes are located in the inner elbow. They drain lymph from the forearm and hand. Swelling in these nodes, called epitrochlear lymphadenopathy, can signal various conditions. These include:
Hand infections (especially the medial three fingers)
Cat scratch disease
Syphilis
Leprosy
Leishmaniosis
Tuberculosis
Filariasis
Lymphoma
Malignant melanoma
Hodgkin lymphoma
Non-Hodgkin lymphoma
Acute lymphadenitis (from skin infections or IV drug abuse)
Sarcoidosis-related lymphadenitis
Metastatic lymphadenopathies
Torso and Abdominal Lymph Nodes

The torso and abdominal regions contain central filtration hubs. These nodes monitor internal organ health. The abdomen alone holds a high concentration of lymph nodes, up to 250.
Mediastinal Lymph Nodes
Mediastinal lymph nodes are located around the heart and lungs within the chest cavity. They drain lymph from the lungs, esophagus, and heart. Enlargement of these nodes can indicate various conditions. These include:
Sarcoidosis
Primary lung cancer
Cancer spread from other sites (e.g., esophageal, breast, thyroid cancer)
Mediastinal lymphoma
Kaposi sarcoma
Non-lymphomatous pulmonary lymphoid disorders (e.g., Castleman disease)
Infections (e.g., pulmonary infection, tuberculosis, fungal infection, histoplasmosis)
Occupational lung disease (e.g., silicosis, coal worker’s pneumoconiosis)
Smoking
Interstitial lung disease
Rheumatoid arthritis (rare)
Scleroderma / CREST syndrome
Congestive cardiac failure
Thoracic amyloidosis
Medication-related issues (e.g., phenytoin, methotrexate)
Lower respiratory tract infection
Inflammatory or autoimmune conditions
Chronic obstructive pulmonary disease (COPD)
Cystic fibrosis (CF)
Coccidioidomycosis
Certain autoimmune diseases (e.g., lupus)
Abdominal and Pelvic Lymph Nodes
Abdominal and pelvic lymph nodes are crucial for internal organ health. These Lymph Nodes Locations include mesenteric nodes around the intestines, para-aortic nodes along the aorta, and iliac nodes in the pelvis. They drain lymph from abdominal organs, intestines, and reproductive organs.
Lower Body Lymph Nodes
This section details the lymph nodes responsible for filtering lymph from the legs and groin area. They play a crucial role in lower limb and genital health.
Inguinal Lymph Nodes
Inguinal lymph nodes are located in the groin. They drain lymph from the legs, external genitalia, and lower abdominal wall. These nodes include both superficial and deep inguinal nodes. Swelling in these nodes can signal various health issues.
Common causes of swollen inguinal lymph nodes include:
Infections:
Fungal infections like athlete’s foot or jock itch.
Skin infections such as cellulitis.
Sexually transmitted infections (STIs) like genital herpes, gonorrhea, syphilis, or HIV.
Urinary tract infections (UTIs).
Other infections like cat scratch disease or mononucleosis.
Inflammation: Lymphedema can cause swelling.
Autoimmune disorders: Less common causes include lupus or sarcoidosis.
Cancer: Rare cases involve melanoma affecting the lower body, testicular cancer, ovarian cancer, lymphoma, or leukemia.
Medications: Certain drugs, such as allopurinol or atenolol, can sometimes lead to swelling.
Popliteal Lymph Nodes
Popliteal lymph nodes are located behind the knee joint. They drain lymph from the lower leg and foot. Enlargement of these nodes can indicate specific conditions.
Conditions associated with popliteal lymph node enlargement include:
Infections: Bacterial, viral, or fungal infections in the lower leg or foot. Severe pyogenic infections of the distal lower extremity or knee joint can also cause swelling.
Autoimmune conditions: Sarcoidosis and rheumatoid arthritis are examples.
Lymphoproliferative conditions: Hemophagocytic lymphohistiocytosis can affect these nodes.
Cancers: Lymphomas, leukemia, and other cancers can spread to these Lymph Nodes Locations. Metastasis from other cancers is also a possibility.
Noninfectious diseases: Diseases of the reticuloendothelial system can cause enlargement.
Inflammatory reactions: An inflammatory reaction from an infection around the lymph nodes or in the foot can lead to swelling.
The lymphatic system and its strategically placed lymph nodes serve as the body’s essential immune checkpoints. Understanding these lymph nodes locations empowers individuals to recognize their body’s signals and potential health changes. People should consult healthcare professionals if they notice persistent swelling or other unusual changes in their lymph nodes.


