For 2026, you’ll want solutions that clean, disinfect, and hydrate your lenses effectively. Boston SIMPLUS suits RGP and scleral lenses, while Clear Care’s peroxide system offers a deep clean for soft and rigid lenses. Opti-Free Puremoist provides all-day moisture for soft lenses, with Biotrue and Renu Advanced enhancing hydration for long wear. Each matches specific lens types and comfort needs. Keep exploring to find the best fit for your routine and lens care.
| Boston SIMPLUS Multi-Action RGP Lens Solution 3.5oz |
| Best for RGP Lenses | Lens Compatibility: Rigid gas permeable (RGP), scleral, ortho-k lenses | Cleaning & Disinfecting Action: Cleans, disinfects, removes protein without separate cleaner | Included Lens Case: Not specified | VIEW LATEST PRICE | Read Our Analysis |
| Clear Care Disinfecting Lens Cleaning Solution Twin Pack |
| Deep Clean Power | Lens Compatibility: All soft contact lenses, rigid gas permeable (RGP) lenses | Cleaning & Disinfecting Action: Hydrogen peroxide bubbling action with triple cleaning/disinfecting | Included Lens Case: Yes, exclusive lens case with platinum disc | VIEW LATEST PRICE | Read Our Analysis |
| Opti-Free Puremoist Contact Lens Cleaning Solution 2oz |
| All-Day Moisture | Lens Compatibility: All silicone hydrogel and soft contact lenses | Cleaning & Disinfecting Action: Cleans, disinfects, eliminates microorganisms causing infections | Included Lens Case: Yes, includes lens case | VIEW LATEST PRICE | Read Our Analysis |
| Biotrue Multi-Purpose Contact Lens Solution 10oz |
| Natural Comfort Boost | Lens Compatibility: Soft contact lenses including silicone hydrogel lenses | Cleaning & Disinfecting Action: Cleans, conditions, hydrates, disinfects, removes protein and debris | Included Lens Case: Yes, includes lens case | VIEW LATEST PRICE | Read Our Analysis |
| Renu Advanced Multi-Purpose Contact Lens Solution 12oz |
| Trusted Daily Care | Lens Compatibility: Soft lenses including silicone hydrogel lenses | Cleaning & Disinfecting Action: Multi-purpose cleaning, triple disinfectant action, removes protein | Included Lens Case: Yes, includes lens case | VIEW LATEST PRICE | Read Our Analysis |
More Details on Our Top Picks
Boston SIMPLUS Multi-Action RGP Lens Solution 3.5oz
Provided that you wear scleral, ortho-k, or any rigid gas permeable lenses, Boston SIMPLUS Multi-Action Solution is designed to simplify your daily care routine. This all-in-one 3.5 oz bottle cleans, disinfects, conditions, cushions, and rinses your lenses without needing a separate cleaner. It removes daily protein buildup efficiently, so you won’t have to worry about weekly protein removals. Trusted by eye doctors and made by Bausch + Lomb, this solution supports comfortable lens wear and hydration. Through using Boston SIMPLUS, you guarantee your lenses stay clear and your eyes healthy every day with minimal effort.
- Lens Compatibility:Rigid gas permeable (RGP), scleral, ortho-k lenses
- Cleaning & Disinfecting Action:Cleans, disinfects, removes protein without separate cleaner
- Included Lens Case:Not specified
- Size (Fluid Ounces):3.5 fl oz
- Moisture/Comfort Benefits:Conditioning and cushioning for comfort and hydration
- Brand/Manufacturer:Boston (Bausch + Lomb)
- Additional Feature:No weekly protein removal
- Additional Feature:Cushions and hydrates lenses
- Additional Feature:#1 eye doctor recommended
Clear Care Disinfecting Lens Cleaning Solution Twin Pack
In case you want a thorough clean that tackles dirt, protein, and debris, Clear Care Disinfecting Lens Cleaning Solution Twin Pack is a reliable choice. Each twin pack includes two 12 fl oz bottles and an exclusive lens case with a platinum disc. This disc activates the hydrogen peroxide bubbling action, providing powerful triple action that loosens dirt, deep cleans, and removes protein buildup. The solution safely neutralizes into gentle saline, making it compatible with all soft and rigid gas permeable lenses. Keep in mind, never apply the solution directly to your eyes and always follow the instructions carefully for safe, effective use.
- Lens Compatibility:All soft contact lenses, rigid gas permeable (RGP) lenses
- Cleaning & Disinfecting Action:Hydrogen peroxide bubbling action with triple cleaning/disinfecting
- Included Lens Case:Yes, exclusive lens case with platinum disc
- Size (Fluid Ounces):2 x 12 fl oz (twin pack)
- Moisture/Comfort Benefits:Converts to gentle saline after bubbling for comfort
- Brand/Manufacturer:Clear Care (Alcon)
- Additional Feature:Hydrogen peroxide bubbling
- Additional Feature:Platinum disc activation
- Additional Feature:Converts peroxide to saline
Opti-Free Puremoist Contact Lens Cleaning Solution 2oz
Should you wear silicone hydrogel or other soft contact lenses, Opti-Free Puremoist Contact Lens Cleaning Solution offers a reliable daily care routine through effectively cleaning and disinfecting your lenses. This #1 doctor-recommended solution eliminates microorganisms that can cause infections while surrounding your lenses with the HydraGlyde Moisture Matrix for all-day comfort. It also creates a barrier to reduce deposits and debris, keeping your lenses fresh. Designed for routine use, it cleans, disinfects, and stores your lenses safely in the included case. Opti-Free Puremoist guarantees your lenses stay comfortable and hygienic every day.
- Lens Compatibility:All silicone hydrogel and soft contact lenses
- Cleaning & Disinfecting Action:Cleans, disinfects, eliminates microorganisms causing infections
- Included Lens Case:Yes, includes lens case
- Size (Fluid Ounces):2 fl oz
- Moisture/Comfort Benefits:HydraGlyde Moisture Matrix for all-day comfort
- Brand/Manufacturer:Opti-Free (Alcon)
- Additional Feature:HydraGlyde Moisture Matrix
- Additional Feature:Eliminates infection microorganisms
- Additional Feature:Reduces deposits and debris
Biotrue Multi-Purpose Contact Lens Solution 10oz
In case you often wear soft or silicone hydrogel contact lenses, Biotrue Multi-Purpose Contact Lens Solution 10oz is designed to keep them clean and comfortable throughout your day. It cleans, hydrates, and disinfects your lenses while removing protein and debris. Thanks to hyaluronan, a natural moisturizer, it provides up to 20 hours of moisture and matches your tears’ pH for better comfort. Whether you’re storing or rinsing your lenses, this solution supports prolonged wear and eases dryness, especially during digital device use. Plus, it comes with a lens case, making your lens care routine simple and effective.
- Lens Compatibility:Soft contact lenses including silicone hydrogel lenses
- Cleaning & Disinfecting Action:Cleans, conditions, hydrates, disinfects, removes protein and debris
- Included Lens Case:Yes, includes lens case
- Size (Fluid Ounces):10 fl oz
- Moisture/Comfort Benefits:Up to 20 hours moisture, pH matched to tears, contains hyaluronan
- Brand/Manufacturer:Biotrue (Bausch + Lomb)
- Additional Feature:Contains natural hyaluronan
- Additional Feature:Matches tear pH balance
- Additional Feature:Up to 20 hours moisture
Renu Advanced Multi-Purpose Contact Lens Solution 12oz
Whenever you regularly wear soft or silicone hydrogel lenses, Renu Advanced Multi-Purpose Contact Lens Solution 12oz offers a thorough care routine that cleans, disinfects, and hydrates your lenses for up to 20 hours. Trusted among over a million households, this Bausch + Lomb product features triple disinfectant action to prevent protein buildup and keep your lenses fresh. Its advanced formula conditions, cleans, rinses, and removes deposits while providing lasting moisture to combat dryness. The 12-ounce bottle includes a convenient lens case, making it a reliable, all-day comfort solution for maintaining your contact lenses effectively and easily.
- Lens Compatibility:Soft lenses including silicone hydrogel lenses
- Cleaning & Disinfecting Action:Multi-purpose cleaning, triple disinfectant action, removes protein
- Included Lens Case:Yes, includes lens case
- Size (Fluid Ounces):12 fl oz
- Moisture/Comfort Benefits:Up to 20 hours moisture, hydrates, prevents dryness, all-day comfort
- Brand/Manufacturer:Renu (Bausch + Lomb)
- Additional Feature:Triple disinfectant action
- Additional Feature:Trusted by 1M+ households
- Additional Feature:Prevents end-of-day dryness
Factors to Consider When Choosing Contact Lens Soaking Solutions
Upon selecting a contact lens soaking solution, you need to evaluate how well it works with your specific lens type and its cleaning and disinfection abilities. You’ll also want to reflect on how it affects lens hydration and comfort throughout the day. Finally, ease of use can make a big difference in your daily lens care routine.
Lens Type Compatibility
Because different contact lenses have unique materials and structures, you’ll need to choose soaking solutions that match your lens type to guarantee proper care and comfort. Rigid gas-permeable (RGP) and scleral lenses require solutions designed specifically for gas-permeable materials to condition and protect their stiffer surfaces. Soft and silicone hydrogel lenses usually work well with multi-purpose solutions that clean, disinfect, and maintain moisture. Hydrogen peroxide-based systems suit most lenses but must be neutralized before wearing to avoid irritation. Not all daily cleaners or protein removers fit every lens type, so always check compatibility with your specific lens—whether soft, silicone hydrogel, RGP, or scleral. For specialty lenses like orthokeratology or hybrid, follow manufacturer recommendations to maintain fit and performance.
Cleaning Effectiveness
Choosing the right soaking solution goes beyond matching it to your lens type—you also need to take into account how effectively it cleans. Look for solutions that explicitly remove protein deposits and loosen dirt, as buildup can reduce clarity and comfort. Check for demonstrated antimicrobial activity to reduce infection risk. Understand whether the solution uses mechanical cleaning, like enzymes or surfactants targeting deposits, or chemical methods, which differ from disinfection. Pay attention to claims such as “daily protein remover” or “triple-action cleaning,” and seek supporting lab data showing deposit reduction. Finally, confirm the solution’s cleaning efficacy aligns with your specific lens material—soft, silicone hydrogel, RGP, or others—since effectiveness can vary depending on lens surface properties. This guarantees your lenses stay clean and comfortable.
Disinfection Power
Evaluate the disinfection power of your contact lens solution carefully to make certain it effectively eliminates harmful microorganisms. Effective solutions achieve at least a 3-log (99.9%) to 6-log (99.9999%) reduction of bacteria and fungi within the recommended soak time. Keep in mind that different active agents, like hydrogen peroxide or multipurpose disinfectants, work through distinct mechanisms affecting how quickly and broadly they kill microbes. Always follow the recommended soaking duration—shorter times might leave viable microbes on your lenses. Some systems require a neutralization step to make residues safe for your eyes, so use the correct case and protocol to avoid irritation. Also, bear in mind that organic soil and protein deposits can reduce disinfection performance, so cleaning or rubbing lenses before soaking improves the solution’s effectiveness.
Hydration and Comfort
You’ll often find that hydration and comfort play a essential role in how enjoyable your contact lens wear feels throughout the day. Whenever choosing a soaking solution, look for ones advertising long-lasting moisture or hydration technology to keep your lenses wet and reduce dryness via day’s end. Solutions with ingredients mimicking natural tears, like lubricants or humectants, improve initial comfort and minimize friction between your eyelids and lenses. Some products specify moisture duration—“up to 20 hours” in lab tests—signaling extended hydration. Proper conditioning agents also prevent deposit buildup and help lenses retain moisture, which is imperative provided you spend hours on digital devices or wear lenses for extended periods. Should dryness bothers you often, pick a multi-purpose solution that hydrates and conditions lenses during cleaning and storage, rather than relying just on rewetting drops.
Usage Convenience
While comfort and hydration are essential, convenience plays a big role in how easily you stick to your lens care routine. Opt for a multi-purpose solution should you want to simplify tasks like cleaning, disinfecting, rinsing, and storing with just one bottle. Check whether the solution includes a lens case or needs activation steps, since these can add time to your routine. Also, be aware of whether you’ll need separate protein removal treatments weekly or daily. Assuming you spend long hours in lenses or use digital devices, pick solutions that offer extended moisture to reduce the need for rewetting drops. Considering these factors, you can choose a solution that fits your lifestyle and keeps your routine hassle-free.
Packaging and Size
Alongside convenience in use, the packaging and size of your contact lens solution can greatly impact your daily routine. Choose a bottle size that fits your habits—small (2–4 fl oz) for easy travel or larger (10–12 fl oz) to minimize how often you repurchase at home. Decide between multi-dose bottles, which are cost-effective for daily wearers, and single-use vials that cut contamination risk, especially should you have sensitive eyes or travel frequently. Look for packages that include lens cases or activation devices, especially for peroxide systems, so you don’t need extra purchases. Check expiration dates and avoid buying large amounts unless the shelf life is short. Also, pick bottles with secure, easy-to-control dispensers like pumps or droppers to prevent waste and contamination during handling.
Safety and Warnings
Because improper use of contact lens soaking solutions can cause serious eye issues, you must follow the manufacturer’s instructions carefully. Always stick to recommended soak times and neutralization steps to guarantee proper disinfection and avoid chemical injury. Never put unneutralized hydrogen peroxide solutions directly in your eyes or wear lenses before neutralization—residual peroxide can cause severe irritation or corneal damage. Wash your hands thoroughly and handle lenses over a clean surface to prevent contamination. Replace your lens case every 1–3 months to reduce microbial buildup. Always discard old solution instead of topping it off or reusing it, since diluted or aged solution won’t disinfect effectively. Should you experience redness, pain, blurred vision, unusual discharge, or persistent irritation, stop using the solution and consult your eye care professional immediately.
Brand Reputation
Upon selecting a contact lens soaking solution, you should prioritize brands with a strong reputation built on proven experience and professional endorsements. Choose manufacturers with a solid track record in eye-care products, as their longer industry presence means better testing and regulatory compliance. Look for recommendations from eye-care professionals and clinical guidelines, which signal real-world effectiveness. Favor brands that openly share safety data, ingredient lists, and clinical studies, guaranteeing transparency and accountability. Also, pick companies offering clear user instructions, customer support, and recall procedures, reflecting their commitment to consumer safety. Finally, verify reputation through independent reviews, regulatory feedback, and peer-reviewed research rather than marketing claims alone to secure you select a reliable, trustworthy solution for your lenses.